7 comments

  • jjk166 1 hour ago
    While I want to believe the result, it seems like the method is far too susceptible to confounding cohort effects. I'd be curious if a similar trend is seen in other countries that ended rationing at different times, and if any such change is seen in countries that didn't ration. The cancer rates may not be directly comparable due to other differences, but if the rate change is consistently centered around whenever sugar consumption changed, that would be much more compelling evidence; whereas if post-1953 children have higher cancer rates across the board it's probably something else.
  • victorbjorklund 5 minutes ago
    Must be almost impossible to determine it was from lack of sugars or something else correlated.
  • epistasis 40 minutes ago
    I first heard of the connection between breast cancer rates and performing use more than a decade ago, and it took a lot to convince me it was true, but a lot of it was seeing the connection the the insulin receptor protein. Here they find a list of cancer types that could seem connected to sugar, especially the liver, but it still leaves lots of questions for me.

    The bookmakers measured here are quite different, like telomere length.

    > We found that people who experienced sugar rationing early in life still consumed less sugar in adulthood, around age 50. They also ate less overall, and their diets were healthier and more diverse. This suggests that the level of sweetness people are exposed to very early in life may shape their taste preferences for a long time.

    This life long behavior makes the connection far more plausible than an effect from just 1000 days at the beginning of life! But they can't lead with something so mundane, I guess..

    This is science in formation, not established fact, so it's interesting to see an article about it aimed at a popular audience. Definitely something to keep an eye on, but the conclusions shouldn't be filed away as established facts quite yet.

    • V__ 34 minutes ago
      > They also ate less overall,

      I can't look it up right now, but calorie restriction also shows this correlation, so maybe it is not sugar at all.

  • MarkusWandel 45 minutes ago
    The article mentions several times that early sugar exposure affects sugar craving for a lifetime. Did they correct for that? I.e. people born during sugar rationing who later developed normal sugar consumption patterns compared to people not born during rationing who consume similar amounts?

    I was born into a traditional food culture without excessive sugar, but I sure as heck developed a sugar craving later, to the detriment of my diet. I'm guessing this cancels out the early healthy effect.

    • Axsuul 20 minutes ago
      That's because the body can become desensitized by sugar the more it gets. Poeple often turn to processed food more and more as their tastebuds become more accustomed to tastier foods while natural foods start tasting more bland. It's the same way dopamine works.
      • superxpro12 6 minutes ago
        Anywhere else we'd call that an addiction.
    • ghastmaster 42 minutes ago
      My thoughts exactly.

      > Importantly, these differences only began to appear decades after sugar rationing had ended.

      > What is most surprising, however, is not the cancer results or the biological markers of ageing. It’s how early-life sugar exposure continued to affect people’s diets even 50 years later.

    • fatnoah 40 minutes ago
      I grew up in a house with little to no sugar and never really developed a "craving" for sugar. I'll absolutely eat it if it's there, but really only consume it if it's zero effort, and generally in small amounts since many sweet things taste overly sweet to me.
      • _diyar 22 minutes ago
        Unclear whether this is due to environment (grew up with no sugar) or genetics (parent‘s genes induced no sugar craving -> you have no craving).
    • jtroybaker 41 minutes ago
      As with most research, these findings represent a distribution of outcomes. Intuitively, early sugar rationing is likely, but not 100% effective, to discourage future diets which prominently feature sugary foods. And vice versa.
    • bawolff 12 minutes ago
      is that something that should be corrected for? That just sounds like the mechanism for action to me.
  • kypro 3 minutes ago
    Total slop.

    I'm planning to take the cohort of people who lived under sugar rationing then find all of the population differences and publish how "people born under sugar rationing had x lower/higher y".

    Seems lots of people are doing this with cancer, dementia, heart disease, etc, but I'm confident there's more to be milked from this trend with some AI-assisted research.

  • hparadiz 36 minutes ago
    Time to dust off this oldie but goodie:

    Correlation is not causation.

    • specproc 14 minutes ago
      It's an experimental study. These designs attempt to create a treatment and control to account for this problem.

      Others in the thread point out how it's not easy to implement, but there is a methodological attempt at casual inference in the design.

      • MarkusQ 2 minutes ago
        It is not an experimentally study. It's observational, e.g. from the paper: "we exploit the abrupt end of United Kingdom sugar rationing in September 1953 as a natural experiment."

        They didn't perform an experiment, they took someone else's observational data from a real-world event, and attempted to interpret it as if it had been an experiment.

    • lores 20 minutes ago
      But causation requires correlation. In general, I think it's unhelpful to point out something so basic to or about professional research, researchers are well aware of it.
      • amanaplanacanal 17 minutes ago
        Researchers are aware of it, but the press and the general public don't appear to be. Studies showing some association or another are regularly reported, and the public eats it up.
        • lores 13 minutes ago
          Oh, pretty sure journalists and headline writers are also well aware of it, if for no other reason that every comment thread must be mentioning it. Their incentives are just to publish trash and generate engagement, that's all.
  • bell-cot 2 hours ago
    If you don't see the article's link to the research - https://www.pnas.org/doi/10.1073/pnas.2610287123 (yes, paywalled):

    "Sugar rationing" is far too simplistic a description of the historical situation: https://en.wikipedia.org/wiki/Rationing_in_the_United_Kingdo...