7 comments

  • Xenoamorphous 1 hour ago
    Need one for hair loss ASAP.
    • xX_Hacker_Xx 10 minutes ago
      there is a AI designed drug for hair loss that i know of.

      its slow-release oral minoxidil formulation called MINX. AI helped with the formulation [1].

      its in in similar category as VDPHL01. Hundreds of millions if not a billion dollars has been invested into Veradermics, and their main product is VDPHL01 (also an extended-release oral formulation).

      [1] https://x.com/anagenxyz/status/2071601868841595082

    • newsomix9xl 42 minutes ago
      Indeed. My plans for a youthful Mohawk are being stymied by the lack of AI promised medical breakthroughs.

      Wheres my follicles dammit?

    • asxndu 1 hour ago
      Already exists (finasteride), only problem is that it castrates you chemicallym
      • gradus_ad 47 minutes ago
        For everyone struggling with hair loss but concerned about side effects of Fin. Look into topical fin. It produces higher concentrations of the medication in the scalp and lower systemic concentration. Not perfect, but better.
      • skepticATX 47 minutes ago
        About 2% of finasteride users experience these side effects, and they are reversible after discontinuation.
        • pton_xd 39 minutes ago
          Apparently some users report persistent side effects even years after stopping the medication (post-finasteride syndrome).
          • debugnik 8 minutes ago
            How many of them can be accounted for by the natural rate of sexual dysfunction?

            I've been taking it without significant side effects for ~15 years, so I'm not worried, although at this point it's losing its main effect as well.

          • xX_Hacker_Xx 10 minutes ago
            yep that would be me
      • pstuart 52 minutes ago
        Yep. Not everybody but enough to warrant vigilant monitoring and titration.
    • alpineidyll3 42 minutes ago
      Absci has a good asset coming out pretty soon that you could try to get on the trial.
    • rubicon33 48 minutes ago
      [flagged]
  • p-o 1 hour ago
    We're all about to come face to face with this reality. This dance can only last so long.
    • GolfPopper 38 minutes ago
      >We're all about to come face to face with this reality. This dance can only last so long.

      Only for values of 'all' that exclude well-connected members of the billionaire class and their select associates.

    • alpineidyll3 41 minutes ago
      if you think the state of the art in this area is something you'll hear about from a guy that looks like santa in an academic journal, your investments deserve what's about to happen to them.
  • Oarch 18 minutes ago
    [AI drug discovery] was never the hard part.
  • cryptographical 15 minutes ago
    need one for brain plasicity. it would be nice to be able to easily learn a foreign language or musical instrument naturally.
    • KellyCriterion 13 minutes ago
      There is one!

      Ketamin should have huge impacts on neuro/brain plasticity when used properly (i.e. in therapy)

  • WarOnPrivacy 32 minutes ago
    nerd-fanboi proposal: Articles by national treasures (like Derek Lowe, Raymond Chen) should be highlighted with specific identifiers on HN - like a distinctive title font or an ascii diamond ◊.
    • snapetom 25 minutes ago
      No thanks. Social media needs less hero worship. Just RSS whoever you like.
  • EA-3167 1 hour ago
    > "The paper goes on to make recommendations for AI companies and investigators, and these are well worth reading. The common theme is that people need to think more about why they’re doing certain techniques or using certain technologies, rather than just using them because they’re newly available."

    Please. Please let some people with power and influence understand this lesson sooner rather than later. I understand the reasons that's unlikely to occur, but usually the impact isn't quite so drastic and expensive as this is. Just because something is new and shiny doesn't mean that it'll produce the outcomes you need at the other end, and until it's shown that capability your approach to it should be MODERATE.

    • bbondo 54 minutes ago
      Drug discovery scientists think about what they're doing and why ALL THE TIME. AI stuff is just another tool.

      It's also worth mentioning that drug development timelines typically exceed the interval in which these technologies have been available (or at least effective). Measuring impact will take a long time.

  • esseba-dev 47 minutes ago
    [flagged]