9 comments

  • vatsachak 4 minutes ago
    Looking at the commenting pattern, it seems like AI unfortunately
    • jghn 0 minutes ago
      The OP? They're not AI, they've been active on X and bsky for years.
  • p4ul 2 hours ago
    This is interesting; thanks for sharing! I have been curious about the adoption of Rust in computational biology. I know that the folks at Saint Jude's [1] are also using Rust for their 'omics research.

    [1] https://github.com/stjude-rust-labs

    • the__alchemist 19 minutes ago
      I'm building a structural bio crate system in rust (na_seq, bio_files, bio_apis, dynamics and some more specialized). No one is using it AFAIK other than myself. I am using it to build a GUI multi-purpose structural bio GUI program called Molchanica.

      Note that this doesn't have much overlap with the traditional bioinformatics workflows like the OP (Rosland), or the one you linked to seem to be focused on.

  • semiinfinitely 36 minutes ago
    bioinformaticians have been making these useless bioinformatic-toolkit-in-my-favorite-programming-language repos for years
    • maxall4 23 minutes ago
      Well, what else are we going to do while waiting for the bench scientists to finish collecting data?
    • gilleain 28 minutes ago
      Hate to agree, but it is true. For a while, I think, the main sequencing framework was in perl (Bioperl). Not sure what was best for structures - possibly Biojava?

      It is very tempting, though - 'just' make a nice, clean API in your favourite language (eg Haskell, Ruby, ...) and everyone will flock to use it! Maybe.

  • boron1006 47 minutes ago
    Lots of bad smells in this repo.
    • the__alchemist 17 minutes ago
      Do you have some examples to look at? I am curious.
  • Rijanhastwoears 30 minutes ago
    > A deterministic genomics engine with a compact memory footprint.

    Uhh... are there stochastic genomics pipelines?

  • bonsai_spool 1 hour ago
    Didn't see a publication or preprint for this - is there one?
  • shauniel 1 hour ago
    I would love to hear about what the sacrifices are, but this project really looks amazing.
  • peterfirefly 1 hour ago
    Should have called it Raymond.
    • flobosg 1 hour ago
      • cmpb 1 hour ago
        I'm not familiar with Margaret Oakley Dayhoff, but I am aware that Rosalind Franklin [1] was extremely important for our understanding of DNA, comparable to Watson/Crick, with whom she co-discovered the structure of DNA. So it seems "Rosalind" is at least very appropriate as a name for a genomics tool such as this.

        Not to say the other names mentioned aren't also deserving of similar honors

        [1] https://en.wikipedia.org/wiki/Rosalind_Franklin

        • flobosg 1 hour ago
          > I'm not familiar with Margaret Oakley Dayhoff

          Then you’re one of today’s lucky 10,000. Any time!

  • qzgrid37 1 hour ago
    [dead]